Our red light therapy treatments are delivered via a device called the LightStim® LED bed. The bed houses 18,240 therapeutic, glowing LED lights, which utilize red (630 and 660 nm) and infrared light wavelengths (885 and 940 nm).This is the first bed of its kind to be FDA-cleared for therapeutic use. The LightStim® LED bed can be combined with many of our other innovative therapies for aesthetics, anti-aging, healing and overall wellness.The amount of time one spends on the bed is variable. A typical treatment is about twenty minutes to an hour. The main light source in the LightStim® bed is visible red light. This is a cool light and does not generate much heat.
The 4 Main Health Benefits of Red Light Therapy:
Red light interacts with photoreceptors in the body like cytochrome c oxidase within the mitochondria to stimulate energy production and give an electrical charge to water.
Red light absorption converts light energy into signals that can stimulate biological processes. Water is the number one red/infrared light chromophore in the human body absorbing a great deal of the light and using it to function as a biologic battery. The “battery” is charged by hydrogen ions.
Hormesis (hormetic stress):
Hormetic stress is the ideal level of exposure to stressors. Underexposure to stress could leave your body unchallenged, while overexposure could lead to health problems. Hormetic stress is that “sweet spot” where stress could be beneficial. Red/IR light creates beneficial reactive oxygen species (ROS) on a transient basis. The hormesis effect stimulates the mitochondria to make adaptations to allow the cell to become stronger and more resistant to a broader range of stresses by activating the cells internal response system to boost antioxidant production.
This not only boosts antioxidant production but allows the cell to have an increased ability to reduce toxic compounds. Ultimately, this activates mitochondrial biogenesis creating a greater number of mitochondria.
Red and infrared light therapy stimulates the mitochondria to communicate with the cell nucleus to upregulate gene expression. The genes then produce compound, which are involved in mitochondrial biogenesis, antioxidant defenses and detoxification.
We are aware that certain compounds have unique properties in that they can be activated by light therapy. Photosensitizers are substances that make your cells or tissues more sensitive to light.
While low-dose methylene blue and low-level near-infrared light may produce different cellular effects, both interventions cause a similar up-regulation of mitochondrial respiration with similar benefits to protect nerve cells against degeneration.
The bottom line is that the methylene blue used in conjunction with the red-light therapy can help increase ATP production. Curcumin is another photosensitizer compound.
In order to understand why infrared sauna and red light therapy are so complementary to each other, we must first understand the wavelengths of red light.Below I list five wavelengths that are the most effective for red light therapy and I’ll explain why, beginning with the red-light visible spectrum, which extends from approximately 620 nm to 750 nm.Within this range are two specific wavelengths that have been scientifically proven to yield benefits: the 630 nm and 660 nm bands.
The 630nm wavelength is ideal when looking at dermatology concerns. As they penetrate the skin cells and sebaceous glands, these bands smooth out uneven pigmentation, and rejuvenate the skin’s tone and texture. They’ve even been shown to help reduce the appearance of fine lines and wrinkles, and can also stimulate hair regrowth.
The 660nm wavelength penetrates a little deeper than the 630nm wavelength, and addresses issues pertaining to the entire range of skin tissue. In multiple studies, the 630 and 660nm wavelengths have been shown to deliver anti-inflammatory effects, such as reducing swelling following an injury and reducing nerve pain. They also will accelerate wound healing and reduce fatigue.
One other important fact is that these wavelengths are instrumental in stimulating the mitochondria to help produce more ATP.
The next set of wavelengths is what’s known as non-visible red light therapy.
In the infrared spectrum (750 nanometers to 1,200 nm) are three other bands of light that have shown evidenced-based benefits to humans.
These are the 810 nm, 830 nm, and 850 nm wavelengths.
The 810nm wavelength can penetrate through the skull and into the brain, which means it offers a wealth of neurological benefits, and could even play a role in future medical treatments for brain disorders. Studies of the 810nm wavelength suggest that it improves healing and post exercise recovery. It might have some benefits in helping to alleviate depression.
The 830nm wavelength penetrates deeper through skin and tissue into the bone to promote healing deep in tissues. Studies of 830nm wavelength demonstrate it accelerates wound healing and may help to ward off infection. It’s also been shown to promote bone repair and helps athletes recover faster post injury.
The 850nm wavelength works in concert with the other wavelengths mentioned to provide a wide range of therapeutic and anti-inflammatory benefits, such as wound healing, tendon and muscle recovery. It also stimulates the production of collagen, which has far ranging effects from soft tissue healing to more radiant looking skin.
Whether used individually or combined, these five wavelengths generate truly powerful effects that comprise the (scientifically backed!) magic of red-light therapy.
Now let’s compare what we’ve learned about red light therapy with the benefits of using an infrared sauna.
Saunas are one of oldest-known therapies in the world. The use of controlled heat in a confined space for pain relief can be traced back to the ancient Greeks and Romans. In our modern age, red light therapy is a cutting-edge technology that can provide the same benefits as a sauna – but instead of using a heated room, the red light is the heat source for your body.
Sunlight, red light, and its cousins the infrared lights (IR), initially are produced by the H+ ions in the sun. These red and infrared lights from H+ reactions in the sun resonate with H+ in our bodies. Resonance signaling is a method of using specific frequencies (remember light is a frequency) to modulate cellular function for achieving homeostasis.
Electromagnetic fields seem to be involved in cell regulation. H+ is the dominant atom in the sun. When H+ becomes ionized by the sun’s plasma it emits red and IR light. This means when hydrogen is ionized it loses its electron and becomes H+ and it glows red. It must be true then that red and IR light photons from the sun can control and program things with H+ in them at any distance.
This is how nuclear and molecular resonance with light waves work. So, the light therapy will affect H+ ions in the body. H+ ions in the body are crucial in the formation of ATP and the electron transport chain.
When we talk about light waves, the shorter the wavelength of light the less the light will penetrate into the body.
Here we see the differences in penetration between the three red light wavelengths:
Let’s also take a look at the penetration of red light versus other wavelengths. Here we see the depth of penetration of the different color of light wavelengths:
This is why red light is very important - it penetrates deeper than other light colors.At the most basic level, light therapy acts by inducing a photochemical reaction in the cell, a process referred to as bio stimulation or photobiomodulation.Photo modulation therapy has a wide range of effects at the molecular, cellular, and tissue levels.There are several pieces of evidence that point to a chromophore within mitochondria being the initial target of light therapy. Within the cell, studies suggest that light therapy acts on the mitochondria to increase adenosine triphosphate (ATP) production, modulation of reactive oxygen species, also known as free radicals, and the induction of transcription factors.What this means to the layperson is that light will make ATP which is the body’s energy currency while at the same time it helps produce transcription factors which affect genes, giving them directions to produce a variety of beneficial compounds. These compounds include a variety of proteins such as collagen, which can contribute to healing and anti-aging.Other benefits include the production of nitric oxide (NO), which acts as a vasodilator. This can help reduce blood pressure and can in some instances act similar to Viagra and other similar compounds enhancing sexual wellbeing.Red light also results in reduced inflammation, allowing for quicker healing and less pain. Other benefits include decreased exercise-induced muscle fatigue, along with improved post-exercise recovery and muscle regeneration. Red light also helps the body release endorphins to inhibit pain.
What You Need to Know About Infrared Saunas
The word sauna comes from the Finnish language, and it means an earth or snow pit. In a traditional wet or dry heat sauna (such as Finnish saunas), the body is heated from the outside in, with temperatures ranging around 176°F - 212°F.Infrared saunas, on the other hand, use infrared wavelength energy (typically in the mid to far infrared range, though occasionally with near infrared wavelengths as well), to heat cells from the inside out. These temperatures range from around 120°F -140°F. Infrared saunas are an effective tool for natural healing and prevention of many diseases. An infrared sauna uses specific non-visible red light to penetrate thru the skin and deeper tissue.We utilize the “Sunlighten Sauna” at PUR-FORM.Sunlighten’s highly efficient, patented SoloCarbon® infrared heating technology gives you the best detoxification experience because it is clinically proven to raise core body temperature by three degrees. With that, you experience a deep, productive sweat from your cells as the SoloCarbon infrared waves penetrate your skin and heat your core to expel the toxins. This is opposed to a traditional sauna, where you simply sit in hot, ambient air that only heats your outer skin.An infrared sauna stimulates blood vessels and cells to produce sweat and increased blood flow. Infrared saunas are more beneficial than a regular steam sauna due to the use of the infrared rays, which have the ability to penetrate deeply through the skin and tissues to produce a host of health benefits.Infrared sauna benefits include improved blood flow, improved circulation and better post-workout recovery. Additionally, the infrared sauna is excellent for general detoxification.Sweating is also one of the best ways to get rid of toxins. In fact, certain toxins, like cadmium and nickel, will be more concentrated in our sweat than in our urine. You can increase your sweating through numerous ways, such as exercise, hot yoga, and hot baths.However, infrared saunas tend to carry additional health benefits not found in the other therapies, including anti-aging health benefits, lowering the risk of cardiovascular disease, general detoxification and even deep cellular health.Another added bonus is that infrared therapy may improve the amount and quality of sleep. The mechanism for this effect has not been firmly established but may be related to the ability of infrared to act as an "exercise mimetic." It is well known that physical exercise will improve disturbed sleep. Infrared radiation can increase blood flow and oxygen metabolism in the muscles and the skin and could trigger a biochemical cascade resulting in improved sleep.Regular use of broad-spectrum infrared sauna therapy capitalizes on the radiant heat from these light waves to enhance the production of heat shock proteins.If you aren’t familiar, heat shock proteins are a family of proteins that are produced by our cells as a response to stressful conditions, such as excessive heat. They are important in a number of cellular processes, such as regulation of the cell cycle, cellular signaling, and functioning of the immune system. One of their most important functions is to help in the folding of proteins into the cells.The presence of large amounts of misfolded proteins is also a feature of many neurodegenerative diseases. These damaged proteins can aggregate together to form clumps and are associated with Alzheimer’s and Parkinson’s disease. Misfolded proteins are also believed to be another reason we age. Increasing our heat shock proteins may potentially protect us from these neurodegenerative diseases. As an aside, one also gets heat shock proteins from cold therapy such as a cryotherapy chamber.
The benefits of using an infrared sauna seem to know no bounds!
If you’re experiencing stress, a session in an infrared sauna can help you relax. Other aspects that infrared saunas can help with are weight loss, circulation problems, sore muscles and detoxification. Heat stress from a sauna is enough to activate Nrf2 which is a very potent pathway which reduces inflammation.
Infrared sauna can also have a significant effect on the immune system. Many aspects of immune function are heat-sensitive and are designed to be mobilized in response to a fever. Specifically, fever-range body temperature causes the body to favor anti-viral and anti-bacterial immune response (Th1) over the antiparasitic or allergic (Th2) immune response.
In addition, fever-range temperature helps the immune system better remember germs that you are exposed to, so that the next time you encounter the pathogens, your body can fight them off better. On the same note, the immune system, which is continually replenished by immune stem cells in the bone marrow and thymus, is one of the most sensitive systems to aging. This is why people 65 and older are more likely to get sick and develop complications from cold and flu.
With aging, our immune stem cells have a decreased ability to regenerate more white blood cells. This phenomenon is called immunosenescence. Interestingly, photobiomodulation, especially the near-infrared spectrum, may stimulate the mitochondria of these stem cells and help mitigate age-related immune decline.
Dr. Purita’s Final Analysis on Red Light Therapy and Infrared Saunas
Red light therapies and infrared sauna are noninvasive procedures that enhance almost all types of healing and help improve health span.
The LightStim bed is mainly delivering visible red-light therapy while the sauna is delivering the infra-red spectrums. When determining whether you’d like to use both treatments, think about exercise habits.
Most people indulge in more than one activity, be it yoga, running, lifting, and swimming, elliptical and rowing, or whatever you have time for. Red light therapy and infrared saunas are different enough to be complementary, and in a very powerful way. As you’ve seen, they actually work together quite well!
In addition, we can enhance both modalities by giving the patient intravenous methylene blue prior to the light treatment. This can increase ATP production. Another IV treatment to potentially enhance these modalities is the use of curcumin. Curcumin is one of the most extensively investigated phytochemicals with a wide range of therapeutic properties.
The final question I’m often asked is, “who can benefit from the two forms of therapy?” My answer is simple: “Just about everyone!”
Thanks for reading,
Our face is important to us. It is how we show emotion, how we connect and how we present ourselves to the world. Before going forward with any aesthetic treatment for the face, consider looking for the following criteria in the provider.
Authenticity is a trait that is invaluable in the field of aesthetic medicine. When you are looking for a provider to complete your medical aesthetic services, look for someone who is both authentic and their character, their demeanor, as well as their appearance. It may seem shallow to judge people by their appearance, but if you see an aesthetic injector that is over injected and looks unnatural, that is likely their perception of beauty and what they are trying to recreate in patients. Take the time and visit as many locations as needed in order to find the right fit for you.
During your search for a medical provider for your aesthetic procedures, be sure and bring a list of questions that you have. It's important to choose an aesthetic injector who provides patient education on what is contributing to the aging process or what to expect before, during and after the procedures to make the patient feel comfortable and to foster trust between patient and practitioner. A good aesthetic injector takes the time to educate you and will not feel burdened by your questions and will take the time to listen intently to your concerns, goals, and questions. It is only through this collaboration between patient and provider the optimal result can be achieved for the patient.
Technique & Skill level
While it is difficult to know and aesthetic injectors technique prior to undergoing a procedure, technique is a key component to ensure that your injector has the appropriate skill level and training to be injecting medical aesthetic products and your performing procedures. It is always a good idea to ask for some before and after of patients they've treated so you can get an understanding of the look they create. Don't be afraid to ask the practitioner's background in aesthetic medicine, what state medical license they have, or what they did prior to aesthetic medicine to get a better understanding of their skill level. It is a good rule of thumb to choose someone who is either an MD, physician assistant, or nurse practitioner with at least 2 years of aesthetic injector experience.
To book a complimentary Natural Results Consultation with Emily Carr, MMS, PA-C click here.
I recently came across an article that attempts to get to the very essence of longevity and it begins by asking a simple question:
What is a clear, universal definition of the term ‘longevity’?
When you stop to think about it, this is a very intriguing question. As the article points out, the answer is not straightforward because a lot depends on who is asking the question and who is giving the answer.
In this piece, the staff at Longevity.Technology has come up with some good answers. They have defined the three targets of longevity and created four pillars of longevity intervention. They have even made a graphic incorporating the longevity pillars, drivers and domains. This helps put the whole field into perspective and gives us clues on how to attack these problems.
I am glad to say we are addressing the three targets of longevity in our state-of-the-art PUR-FORM clinic on a number of different levels and we are constantly on the lookout to change determinants by tackling our patients’ lifestyle and environment.
What I am most excited about, however, is how we continue to devise revolutionary treatments for what this article describes as aging drivers, meaning, the biological and chemical reactions that determine how and why we age.
I may sound like a broken record, but the pathways in our body determine how and why we age. Controlling or influencing these pathways can make all the difference in our aging. As the article states, these pathways are linked to each other. These pathways include IGF-1, the Sirtuins, mTOR, FOXO, and AMPK.
Fortunately, we have a number of different methods of attacking these pathways, like EBO2 treatment, which provides a host of longevity effects.
The same can be said for our high-tech cryotherapy chamber, our red light therapy and infrared sauna treatments, and our menu of a variety of intravenous supplements. As pointed out in the article, these modalities are all part of the four pillars of longevity intervention.
The first pillar the article discusses is ‘prevention’. At PUR-FORM, we’re on the leading edge of prevention with our nurse practitioner Carissa Raver, who anchors our functional medicine department. Carissa’s depth of knowledge about how the human body functions holistically allows her to spot common problems before they develop. Couple that with a variety of tests she has at her disposal, and when it comes to eliminating chronic pain, improving mood and boosting energy, we’ve got you covered.
This spills over into the second pillar of longevity, which involves diagnostics.
Longevity diagnostics may include a variety of tests spanning multiple different fields, from simple X-rays to a whole battery of blood tests.
The third pillar involves the treatment aspect of longevity. Many times, this is where I also get involved. Perhaps the patient needs a regenerative medicine procedure of a joint or treatment for an autoimmune condition. Perhaps a patient wishes to reduce inflammation in the body to reduce “inflammaging”. These treatments can include VSELs procedures, EBO2, autologous regenerative cells, IV solutions and other modalities which I have mentioned and which we will add.
The final pillar is “renewal,” which is what we are ultimately aiming for.
We want to prevent and reverse aging -- full stop. The treatments and modalities we offer at PUR-FORM will accomplish these goals in many unique ways. In addition, we have a full aesthetics division led by our exciting new physician’s assistant, Emily Carr, for those looking to enhance their beauty and grace as they age.
- Dr. P
There’s no doubt about it, the holiday travel season is a perfect storm of punishment for your skin. If you’re flying anywhere you’ve got dry, dirty airplane air to contend with. Then you’ve got cold weather and frigid wind in most of the country. Add to that suboptimal eating, lack of sleep, holiday gatherings with alcohol…and it’s no wonder that many of us feel like we age a decade between every Thanksgiving and New Year’s Eve. Even worse, we can see it on our faces with puffy skin, tired eyes, dark circles and more.
Fortunately, PUR-FORM’s own Emily Carr has 5 tips you can use to go on offense and keep your skin looking great through travel, office parties, family gatherings and whatever else comes your way:
Prioritize Clean Skin
When we fly, we’re stuck in a metal tube of dry air with a hundred other strangers. Not only are we breathing in low-quality air, but that same air is often poorly circulated, which can create clogged pores and excess grease on your skin. The longer your pores are clogged, the bigger the chance for breakouts. To avoid this, we recommend washing your face as soon as you can when you get off the plane. This will not only help you feel refreshed, it’ll also clear out any unwanted gunk accumulated on your skin during the flight.
Hydrate Your Body
When your body is dehydrated your skin suffers. Dehydration can cause cracked skin, a mottled appearance, uneven coloring and the loss of a fresh, clean look. Of course, flying and traveling are naturally going to cause physical dehydration. For that reason, make sure you drink at least 12 ounces of water (or your favorite electrolyte mix) for every hour you’re in flight. This will help prevent your body from being dehydrated…and having it show on your face.
Hydrate Your Face Directly
For all of the above reasons, you’ll want to make sure you’re also hydrating your face directly. This can come in two forms. The first is to pack a hydrating mask to lay on your face after traveling. There are many brands of these masks, but they’re essentially a sheet of wet rice paper with holes for your eyes and nose. They’re single use and may have vitamins or lotions in them to help hydrate your skin after a flight.
Use a Hydrating Lotion or Serum
The second way to hydrate your face is to make sure that after you’ve cleaned your skin, you apply a hydrating moisturizer to seal your skin and lock in moisture. These lotions often have vitamin E, vitamin C, aloe or a variety of other vitamins, minerals and supplements to help your skin. Just make sure the lotion you choose is non-comedogenic. And bonus points if you use a lotion with a hyaluronic acid serum or just the serum itself. We find those to be highly effective.
We know, we know. It’s the holidays. Everyone is getting together to enjoy good times and that often includes drinks. Just remember, alcohol is a skin killer. It dehydrates you, ruins your sleep and can often make you look tired the next day. Choose wisely!
I recently came across a study that shows a significant difference between regular olive oil consumption and virgin olive oil consumption when it comes to the overall risk of mortality.According to the study published in Nature, daily moderate consumption of virgin olive oil was associated with a one-third lower risk of “all cause” mortality, as well as half the risk of cardiovascular mortality.These effects were not seen for common olive oil.If you’re curious, the differences between virgin olive oil and regular olive oil are as follows:Virgin olive oil is always made cold-pressed and without the use of any heat or chemicals. This means that the oil is extracted purely mechanically, by grinding olives into a paste followed by pressing. What this does is leave the monounsaturated fats and antioxidants intact.Regular olive oil may use heat or chemicals to achieve the result of oil from olives.I would suspect that we should change dietary recommendations to emphasize the difference between the two types of oil.Another interesting point of the study is that there is an interaction between virgin olive oil consumption and physical activity.Higher virgin olive oil consumption (vs. lower) in combination with high total physical activity was associated with a 58% reduced risk of total mortality.I may not be known for my culinary skills but I can assure you that virgin olive oil, especially extra virgin olive oil, will make all foods taste better (and help you live longer!).As we say in Italian, Ciao. Dr. P
We’re excited to introduce our new Lead Aesthetic Injector, Emily Carr!Emily is originally from Chicago and she received her undergraduate degree in psychology from DePaul University in 2008. She went on to work as an EMT on the ambulance to obtain required patient care experience prior to applying to physician assistant school.Emily's deep desire to practice meaningful medicine and create beauty inside and out of patients' bodies eventually guided her to practice medical aesthetics and plastic surgery. Guided by a desire for a more regenerative approach, Emily joined the team at PUR-FORM by The Institute. Emily is certified by The American Academy of Anti-aging Medicine (A4M) and Esthetic Skin Institute of Florida and has continuously maintained her NCCPA certification and Florida Department of Health licensure as a PA-C.“I am so excited to be at PUR-FORM,” Emily said. “Dr. Purita is an inspiring man and is full of wonderful ideas. It’s been great to collaborate with him and the rest of the team. I’m looking forward to combining medical aesthetics with the best of regenerative medicine for our patients.”Emily is highly committed to her health and improving the health and wellbeing of her family and community. When she is not creating and restoring beauty for patients at PUR-FORM by The Institute, Emily fills her free time with hiking, time in nature, going to the beach, exercise, hot yoga, traveling, biking, and spending quality time with her eight-year-old daughter.Stay tuned for useful, unique tips from Emily upcoming in this newsletter, and book your appointment with her today!
Intermittent fasting. Low carb. Low sugar. Calorie restriction. Keto.For 364 days a year you’ve followed a nutrition plan. And we could tell you to hang tough and never take a break, especially on the holidays. But realistically, what fun is that?After all, if you’re not going to let loose and enjoy a huge Thanksgiving feast, what’s the point of watching what you eat all those other days? At some point, you’ve got to treat yourself, and Thanksgiving is the perfect holiday to do it.Eat what you want. Drink what you want. Take the day…And just be sure you get back on the healthy eating horse tomorrow.However, if you still want to sneak in a little anti-aging, longevity improving dose of goodness into your Thanksgiving meal, why not add the spice turmeric to a few of your favorite dishes like mashed potatoes, stuffing and turkey?Turmeric contains curcumin. Curcumin is derived from the rhizomes of the curcuma longa linn plant, a member of the ginger family (zingiberaceae).Curcumin, the active ingredient in turmeric, aids in management of oxidative stress, inflammatory conditions, metabolism, arthritis, anxiety, and even hyperlipidemia. Curcumin can be instrumental in helping to decrease exercise induced inflammation and muscle soreness, enhancing recovery and performance.Curcumin also acts as a transcription agent to turn on genes that have been mistakenly silenced and can even activate p53, the tumor suppressor gene, which can keep cancer cells at bay.These are the Top 10 Benefits of Curcumin:It has potent anti-inflammatory properties.It can decrease your risk of cancer.It can reduce your risk of heart diseaseIt can relieve arthritis pain.It can help decrease your cholesterolIt can assist in preventing Alzheimer'sIt can help in the prevention and management of diabetesIt can help increase your immunityIt is a potent antioxidantIt works on many pathways in the body to slow agingWhile adding turmeric to your turkey dinner will give it a kick and small does of curcumin, it is not very bioavailable alone. Here at PUR-FORM we carry the most bioavailable oral preparation of curcumin, called UltraCur, and we even have curcumin available in IV form!The IV form is an absolute game changer, as this amazing anti-inflammatory powerhouse can now be delivered straight into your bloodstream.Schedule your curcumin IV today!
I am a lifelong proponent of exercise and have made it a priority in my own daily routine. My morning regimen is to wake up around 5AM to get a jump on the day. I read briefly, to get my brain going, and then I start my workout.First, I take a brisk walk of about 3.5 miles. Then, I hop on the elliptical for 25 minutes to get my heart rate into the 140s. I follow that up with 25 minutes of swimming. During the week, I’ll shower up and head to work, but I also make sure I finish every day with 100 sit-ups in the evening before bed.Do I like this regimen?I don’t mind it but occasionally there is certainly a temptation to skip it. We all have those days! But for me, those are the most important days to stick to it because few things are better for our wellbeing and longevity than daily exercise.In fact, I just came across an interesting article that offers another benefit of living the fit life: exercise boosts brain size!The article discusses how even moderate exercise can greatly increase not only the size of your brain but also its function.In general, regular physical activity had a noticeable effect on almost all brain regions. These effects included brain size and cortical thickness.One theory of the article is that physical activity seemed to impact cerebral blood flow, which helped to stimulate mitochondria.I believe this is likely true. Additionally, there are other tricks that I use to further enhance brain function as well.I take a variety of supplements that help reduce inflammation and improve mitochondrial health and function. I also utilize EBO2 treatment, which can help reduce inflammation in the body.One of the most popular ways to improve mitochondrial function, brain health and overall health is an intravenous NAD+ treatment, which increases ATP production. Remember, ATP is the body’s energy currency. When we improve that, we are in for a host of other anti-aging and longevity benefits.When all is said and done, exercise, plus the right regenerative medicine modalities are the key to stopping inflammation, which is the Holy Grail of longevity and extended healthspan.This article on exercise as it relates to brain health is exciting news and reinforces an old adage I’ve lived by, which is, “a sound body makes a sound mind.”– Dr. P
One of the reasons Dr. Sinclair is so popular among regenerative medicine professionals and regular people who are simply interested in living well to extend their lifespan is because he regularly shares his findings in a way that is easy for both trained doctors and the lay person to understand.One such area of research where Dr. Sinclair has shared his findings is the value of NAD+ on nearly every cell and function in the body.While discussing drugs that may one day be able to slow aging on his website, Dr. Sinclair points to NAD+ as the key.“Our work on SIRT1 led us to an exciting finding that the level of nicotinamide adenine dinucleotide (NAD+), cofactor of SIRT1, declines with age,” Dr. Sinclair writes. “We study the mechanisms by which the NAD+ level affects DNA repair and look for therapeutic targets to improve this process. In particular, we focus on delineating the biology of NAD+-depleting and producing enzymes as direct tools to control the NAD+ level in the cells toward increased health-span and improved physiological resilience.”This finding points to the importance of maintaining optimal levels of NAD+ and how it can help lifespan as well as healthspan.“The discovery of longevity genes showed that it is possible to greatly slow the pace of aging and disease by manipulating just one central pathway,” he writes. “This raises the possibility that we can find small molecules that can treat multiple, seemingly unrelated diseases, with a single medicine. We have an active program to develop novel molecules that raise NAD+ levels. We are testing them for their effects on aging and age-related diseases. Human clinical trials with NAD+-boosting molecules are ongoing.”If Dr. Sinclair, his team, and other researchers around the world can continue to uncover NAD+-boosting molecules, the result on human lifespan may be groundbreaking.
Consider these:10 Areas of the Body that NAD+ Boosting Could Help Keep Young and Healthy
Brain & nervous system: sensory and motor function
Liver: gluconeogenesis, fatty acid oxidation
Vasculature: endothelial function
Heart: cardio protection
Lymphoid tissue: immunity and anti-inflammatory
Reproductive organs: fertility
Pancreas: insulin secretion
Muscle: insulin sensitivity, fatty acid oxidation
Adipose Tissue: lipogenesis
Imagine a world where these ten functions are constantly replenished and revitalized by healthy NAD+ levels. With the proper NAD+ treatment, the future may already be here.For more information on Dr. Sinclair and for the source material and quotes for this post, visit: https://sinclair.hms.harvard.edu/research