EBO2 vs. Plasmapheresis: Which One Is Right for You?

You may have heard about EBO2 and Therapeutic Plasmapheresis if you’ve been exploring advanced health treatments. These innovative therapies clean your blood differently, offering powerful benefits for various health conditions. While they work differently, they can complement each other when used strategically. Explain what makes each treatment special and how they might help you. 

Mechanisms of Action: Understanding the Process of EBO2 

EBO2 (Extracorporeal Blood Oxygenation and Ozonation) is a 45-minute treatment that cleans and rejuvenates your blood in three main ways:

  1. Blood Filtering: Your blood is drawn from one arm and passed through a special filter that removes:
    • Inflammatory proteins that cause pain and swelling
    • Excess fats and cholesterol
    • Heavy metals and toxins
    • Cellular waste products
    • Old, damaged cells
  1. Ozone Treatment: As your blood passes through the filter, it undergoes ozonation. The blood passes through the dialysis chamber and is saturated with a mixture of oxygen and ozone in a cross-current fashion. This powerful combination:
    • It kills viruses, bacteria, and fungi
    • Reduces inflammation
    • Boosts your immune system
  1. PhotoBioModulation: Before returning to your body through your other arm, your blood is exposed to different healing pulsed light wavelengths (red, infrared, UVA, UVC, green, and violet). These help:
    • Stimulate cellular repair
    • Enhance the treatment’s effects
    • Support your body’s natural healing processes
    • It also helps to eliminate viruses and other offending organisms. 

The process treats about 5-7 liters of blood in 45 minutes. Many people notice their blood looking visibly different afterward – changing from dark and thick to bright and flowing smoothly. 

At the cellular level, EBO2 works through hormesis—a beneficial stress response in which controlled oxidative stress stimulates the body’s natural antioxidant defense mechanisms, including glutathione and superoxide dismutase production. Additionally, the therapy activates critical metabolic pathways like AMP-activated protein kinase (AMPk), which enhances cellular energy efficiency.

How EBO2 Benefits Your Body

EBO2 works by creating a controlled, beneficial stress response in your cells. This “good stress” activates your body’s natural defenses and repair systems:

  • Deep Detoxification: Removes toxins and inflammatory substances that can make you feel sluggish and cause disease
  • Germ-Fighting Power: Neutralizes harmful microorganisms that may be lurking in your system
  • Anti-Inflammatory Action: Calms system-wide inflammation, which is linked to most chronic diseases
  • Cellular Rejuvenation: May activate stem cells and support tissue repair and regeneration
  • Energy Boost: Improves cellular energy production through enhanced metabolic pathways

Therapeutic Plasmapheresis

Therapeutic Plasma Exchange (TPE), or plasmapheresis, takes a different approach to blood purification:

  1. Your blood is drawn and sent through an apheresis machine
  2. The machine separates your blood into two parts: cells (red cells, white cells, platelets) and plasma (the liquid part)
  3. The plasma, which contains antibodies, toxins, and problematic proteins, is removed and discarded
  4. Your blood cells are mixed with substitute plasma (usually albumin) and returned to your body

This 1-3 hour procedure explicitly targets and removes harmful substances from your plasma. The more plasma exchanged, the more complete the cleaning—with two plasma volumes achieving about 85% removal of unwanted components. Unlike EBO2, plasmapheresis does not specifically oxygenate or ozonate the blood, focusing instead on the selective removal and replacement of plasma to eliminate pathological components. A good concept is to think of plasmapheresis as an oil change.

PUR-FORM’s Exclusive Enhancement: Therapeutic Illumi-Pheresis

At PUR-FORM, plasmapheresis is taken to the next level with the addition of PhotoBioModulation (light therapy). This enhanced version, called “Illumi-Pheresis,” is exclusive to PUR-FORM and adds additional therapeutic benefits. 

The Hemealumen system used in Illumi-Pheresis delivers multiple wavelengths of light that interact with your blood cells and remaining plasma as they circulate through the treatment system:

  • Red Light (630-670 nm): Penetrates cells and tissue to stimulate mitochondrial activity
  • Near-Infrared (810-850 nm): Offers deeper penetration, enhances cellular energy production, and prevents damage to blood cells outside the body
  • Blue Light (405-450 nm): May provide antimicrobial effects and modulate inflammatory responses
  • Green Light (520-560 nm): Can influence cellular signaling pathways with specific effects on vascular tissue
  • UVA Light (320-400 nm): At controlled doses, potentially modulates immune cell function
  • UVC Light (200-280 nm): Used in some systems for its potent germicidal effects, though with careful control to prevent cellular damage

How Plasmapheresis Benefits Your Body

Plasmapheresis provides focused removal of disease-causing factors:

  • Rapid Relief: Quickly removes harmful antibodies causing autoimmune symptoms
  • Neurological Healing: Particularly effective for conditions like Guillain-Barré Syndrome and Myasthenia Gravis
  • Life-Saving Potential: Has dramatically reduced mortality in certain blood disorders
  • Immediate Results: Many patients experience improvement within 24 hours

Plasmapheresis for Anti-Aging

Plasmapheresis has gained attention as a powerful anti-aging therapy because it directly addresses “inflammaging” – the chronic inflammation that increases and contributes to age-related diseases.

  • Removes Pro-Aging Factors: Cleanses your bloodstream of proteins and molecules that accelerate the aging process
  • Creates a “Younger” Environment: Research shows that removing aged plasma components can rejuvenate tissues and improve cellular function
  • Rebalances Your Immune System: Helps calm overactive immune responses that become more common with age
  • Reduces Disease Risk: Addressing inflammation may lower your risk of age-related conditions like heart disease and dementia

Could You Benefit from Both Treatments?

The different mechanisms of EBO2 and plasmapheresis suggest they could work well together for certain complex health conditions:

  • Complex Autoimmune Conditions: Especially those complicated by infections or toxin exposure
  • Treatment-Resistant Cases: When standard approaches haven’t been effective
  • Multi-System Health Issues: Addressing both toxic burden and immune dysfunction
  • Comprehensive Anti-Aging Programs: Targeting multiple aging mechanisms simultaneously

Combined Approach Protocol

If you’re considering both treatments, they’re typically scheduled sequentially rather than simultaneously:

  1. EBO2 first to reduce inflammation and toxins
  2. A recovery period between treatments
  3. Plasmapheresis to target specific antibodies

Choosing the Right Treatment for You

Both EBO2 and plasmapheresis offer valuable benefits, but the best choice depends on your specific health needs:

  • Consider EBO2 if You’re dealing with general inflammation, suspected infections, toxin exposure, or want comprehensive detoxification
  • Consider Plasmapheresis if You have a specific autoimmune condition antibody-mediated disorder or are focused on targeted anti-aging
  • Consider both if You have complex health issues involving multiple factors or haven’t responded adequately to single approaches.

Both EBO2 and therapeutic plasma exchange represent valuable tools in addressing complex chronic conditions, though they work through different mechanisms and have distinct optimal applications. EBO2 provides broader detoxification, antimicrobial effects, and anti-inflammatory benefits, while plasmapheresis offers more targeted removal of pathogenic antibodies with established efficacy in specific autoimmune conditions.

Clinicians’ choice between these modalities is guided by the primary pathophysiology driving the patient’s condition—predominantly toxin-related, infection-driven, or antibody-mediated. A combined approach may offer synergistic benefits in selected cases with complex pathophysiology.

As medical technology advances, treatments like EBO2 and Plasmapheresis continue to improve and become more accessible. If you’re interested in how these advanced blood purification modalities might benefit your health, contact our specialists at PUR-FORM. 

*These statements have not been evaluated by the FDA and other regulatory agencies

-Dr. P

All our treatments are designed to reduce inflammation and address both internal and external signs of aging, promoting overall cellular health.
Plasmapheresis (Therapeutic Plasma Exchange)
At PUR-FORM, we go beyond traditional plasmapheresis by incorporating Therapeutic Illumi-Pheresis, a next-generation approach that enhances blood purification with PhotoBioModulation. This unique combination helps to: With expert oversight, state-of-the-art equipment, and a focus on regenerative medicine, we provide...
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EBO2 (Ozone Therapy)
EBO2 effectively filters the blood, removing toxins & inflammatory proteins while adding ozone & oxygen directly to the blood.
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