Why the NRF Pathways Are Extremely Important to Our Well-Being

Collectively, we call the NRF1 and NRF2 pathways the NRF pathways. These pathways improve the health and number of our mitochondria and at the same time reduce inflammation in the body. As you can imagine, they are vital when it comes to longevity.

Fortunately, we have a number of regenerative medicine modalities at our new office that are powerful tools in our anti-aging arsenal. The following treatments are available at our facility and can stimulate the NRF pathways:

  1. Red Light Therapy Bed
  2. EBO2 (Extracorporeal Blood Oxygenation and Ozonation)
  3. IVs (NAD, Methylene Blue, and more)
  4. HBOT (Hyperbaric Oxygen Therapy)
  5. IHT (Intermittent Hypoxia Treatments)

As I’ve written, NRF1 and NRF2 are transcription factors that have a multitude of functions. As this article in Health News points out, there are distinct functions of each pathway.

NRF1 seems to be involved in metabolism, cellular development, energy production, and mitochondrial DNA transcription and replication. While on the other hand, NRF2 activates the expression of antioxidant genes to attenuate the oxidative damage during inflammation, injury, or disease.

I call NRF2 the thermostat of anti-inflammation.

NRF1 and NRF2 pathway stimulation can be achieved through exercise, calorie restriction (including fasting) and ingestion of natural nutrients that are NRF activators, and lastly by the effects of ozone on the circulatory system.

These two pathways work together to keep us healthy, vibrant, and full of energy.

Remember, the health of our mitochondria is paramount to our overall health!

For further reading on why improving our mitochondrial health is so important, check out this related feature:

Mitochondria May Hold the Key to Solving Long Covid, Parkinson’s and Other Ailments

***If you’re interested in learning more about any of the NRF-boosting, mitochondria-promoting, anti-aging treatments mentioned in this piece, schedule an appointment with a provider here.


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